tag:blogger.com,1999:blog-714028479313834812.post7902221561342700949..comments2024-03-28T11:58:42.109-07:00Comments on Raconteur Report: Field Clinical Report: Nawlins ERAesophttp://www.blogger.com/profile/07834464741531503378noreply@blogger.comBlogger34125tag:blogger.com,1999:blog-714028479313834812.post-83172047163173667692020-03-30T17:40:15.166-07:002020-03-30T17:40:15.166-07:00Aesop, as I understand it, having followed this sa...Aesop, as I understand it, having followed this saga since late January, the hydroxychloroquine, zinc, & Zpak should be prescribed the moment a person gets a sore throat, fever & cough while they are not home. Not when they're gasping for air in the ER. Their personal doc should send prescriptions to their pharmacy ASAP. It's meant to be prescribed well before hospitalization is necessary. I am not medically trained, but have been reading the testimony of physicians on this. I'm beginning to think that we're purposely bollixing this up so we have to wait for expensive big pharma meds or that mythical vaccine. <br /><br />Do I think this is some kind of miracle cure? No. But we're not giving it the chance to (we hope) shine in the way that it should - not when some poor soul is intubated and near death, but when they're just showing the 1st symptoms.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-5025011930672091542020-03-29T12:37:11.816-07:002020-03-29T12:37:11.816-07:00Pete B -- I thought chloroquine was as simple as i...Pete B -- I thought chloroquine was as simple as it reduces immune response, the cytokine storm that ultimately kills COVID-19 patients. Older folks immune systems have a hard time shutting off w/ this virus, knowing when it's 86ed, so CQ helps to stop their body's overwhelming attack on the virus from harming other organs.<br /><br />"Chloroquine (CQ), a well-known anti-malarial drug, has long been used for the treatment of autoimmune diseases because of its profound immunomodulatory effects"<br />https://www.ncbi.nlm.nih.gov/pubmed/25477006<br /><br />Accordingly, that's why all anti-antinflammatories are good preventatives for this: NAC, Glutathione, curcumin, ginger, zinc, resveratrol, coQ10, etc. Just google anti-inflammatory supplements.RSRnoreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-6890638931412258962020-03-29T09:48:46.270-07:002020-03-29T09:48:46.270-07:00As others have pointed out, where CQ and HCQ have ...As others have pointed out, where CQ and HCQ have been used to treat Covid-19 patients with good results, it has been used EARLY. Early as in as soon as the patient tests positive or shows up at the hospital with symptoms. As I understand it, it is the Zinc not the CQ that interferes with the viral replication inside the lung cells. But zinc, because of its positive charge cannot get through the gateway into the cell where it is needed. CQ or HCQ opens up the gateway allowing interstitial zinc entry into the cells where it prevents viral replication.<br /><br />However, also as I understand it, for the few hospitals that are even trying it, their protocol is to use the CQ or HCQ only when, in spite of all manner of supportive care, the patient is getting decidedly worse and appears to be headed for a date with a ventilator. By that time the virus has had a week to replicate faster than the Federal Reserve replicates money, and at that point no amount of zinc inside the cells is likely to magically undo the damage and bring the patient back from the brink.<br /><br />These anti-malarial drugs have been around since WWII. The potential side effects are well known, and are mainly of concern for people who are taking them long term, such as cases where they are prescribed off-label for rheumatoid arthritis and certain other auto-immune conditions. In their use for treating Covid-19, the protocol is 500 mg twice a day for ten days. Obviously, Covid-19 patients with significant co-morbidities would need to be monitored very carefully for side-effects. <br /><br />I am in my late 60's, a lifetime non-smoker, not overweight, normal BP and cholesterol, and I take NO prescription meds as I have no conditions for which I would need any. In short, I am in good health, especially for a guy my age. I have never been prone to respiratory ailments of any kind. If I were to get Covid-19, my expectation is that I would be among the 80 percent who have mild symptoms. <br /><br />Nevertheless, if I did develop significant symptoms, I would like to have a 10 day supply of CQ in my medical tool kit, along with the Vitamin C, Vitamin D3, selenium, zinc, etc. If I actually had this virus, I think I would much rather fight it at home with Chloroquine, than be at the hospital with all the related supportive care and NO Chloroquine. I make this statement based on the preponderance of the results where it has been used so far. Again, as long as the HCQ or CQ is administered EARLY ON, it appears to have a good success rate for treating Covid-19.<br /><br />During my annual physical exam last week, I brought this up with my PCP and asked him for a script for CQ. His answer was a flat NO, because "there are no clinical studies yet". Well if I catch Covid-19 next week, and a week after that begin showing all the classic symptoms, I damned well do not agree that I should have to wait for clinical studies before I am able to self-administer a drug that, more often than not, has been shown to help when administered as soon as definite symptoms and/or a positive test occurs. It should by MY choice. As long as I understand and accept the potential risks, I should absolutely have the choice of that course of action, whether at home or in the hospital. <br /><br /> George Truehttps://www.blogger.com/profile/17352709031834067303noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-29779686622330969972020-03-29T08:42:38.687-07:002020-03-29T08:42:38.687-07:00What was said in the piece is that when you take a...What was said in the piece is that when you take all of the patient who’ve been on a ventilator worldwide, 84% died. Seattle counted all of their vented patients total, and 70% died. Its not all patients. Just talking about the ones that got vented.The Gray Manhttps://www.blogger.com/profile/15098168056466325559noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-46586611250568718002020-03-29T08:40:14.270-07:002020-03-29T08:40:14.270-07:00Those things went away after crippling/killing mil...Those things went away after crippling/killing millions and millions of people.The Gray Manhttps://www.blogger.com/profile/15098168056466325559noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-58467329629746578472020-03-29T05:24:17.838-07:002020-03-29T05:24:17.838-07:00The Nawlins Field Report is the top story, highlig...The Nawlins Field Report is the top story, highlighted in red, on Citizens Free Press this morning, 29-MAR @8:20AM<br /><br />NemoAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-2625794192340238752020-03-28T23:41:51.885-07:002020-03-28T23:41:51.885-07:00That was my thought as well...That was my thought as well...Anonymoushttps://www.blogger.com/profile/02157234078890787382noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-29696001348286503712020-03-28T23:25:51.064-07:002020-03-28T23:25:51.064-07:00@Anonymous 5:54:
IF chloroquine works, its effect...@Anonymous 5:54:<br /><br />IF chloroquine works, <a href="https://chrismasterjohnphd.com/can-hydroxychloroquine-or-chloroquine-treat-covid-19" rel="nofollow">its effect is not likely zinc mediated:</a><br /><br />"The best chance for inhibiting viral replication, then, lies in increasing cytosolic zinc, not endosomal zinc.<br /><br />"But chloroquine doesn't increase cytosolic zinc. It traps zinc in lysosomes, where it is irrelevant to viral replication.<br /><br />"So how does chloroquine kill SARS-CoV and SARS-CoV-2 in vitro? Here's what those in vitro papers found:<br /><br />"• It increases endosomal pH. Fusion of the virus with the endosome, and later escape of the virus from the endosome, can both be pH-dependent. Increasing endosomal pH appears to prevent fusion of SARS-CoV with the endosome, and to the extent it makes it in, might also prevent its escape into the cytosol. This is supported by the fact that ammonium chloride, another agent that increases endosomal pH, has the same effect.<br />"• Chloroquine and ammonium chloride also raise the pH in the golgi apparatus, the compartment where sugars are added to proteins in a process known as glycosylation. ACE2, the protein on the cell surface that allows the entry of SARS-CoV and SARS-CoV-2 into the cell, is one of the proteins that are glycosylated in the golgi. Chloroquine and ammonium chloride both interrupt the glycosylation of ACE2. They do not affect the amount of ACE2 on the cell surface, but it is possible that the the virus is less able to dock to ACE2 when the protein hasn't been glycosylated.<br /><br />"Chloroquine raises the pH of the endosomes, lysosomes, and golgi. This is a clearly toxic effect of the drug on human cells, because it will broadly disrupt the ability of the cell to take in things from its environment, digest things that need to be broken down, and glycosylate things that need to be glycosylated. As a result, chloroquine also interferes with the glycosylation of antibodies, which most likely contributes to its ability to treat autoimmune conditions. However, it might also hurt the immune defense against viruses, which might underly why it acted as an antiviral against chikungunya virus in vitro but enhanced viral replication in vivo [in mice].<br /><br />"As noted yesterday, despite the routine use of chloroquine against COVID-19 in China and its incorporation into at least two national guidelines for COVID-19, there is as yet no evidence it is effective."<br /><br />Zinc is best tested in plasma rather than serum. Both suboptimal or insufficient zinc (fairly common) and excessive zinc can impair the immune response, so optimizing zinc status is a reasonable part of your personal health resilience strategy. Zinc supplementation is not a treatment for this infection. We don't understand zinc transport very well; certainly not well enough to manipulate it therapeutically.Peter Bhttps://www.blogger.com/profile/15122781534685443942noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-32700338040926967832020-03-28T18:19:45.443-07:002020-03-28T18:19:45.443-07:00@Adino
So, your house had/has it. Defeated the Fo...@Adino<br /><br />So, your house had/has it. Defeated the Fomites? Not spread it to anyone else? Then your R0 is really 0. At least under 1. Thank you for doing your duty, exemplary and outstanding. Wait a week or two, and you're Vanguard for the Assault on Covid. Replicate yourselves! Hail The Immunes!. Zinc!Stefanhttps://www.blogger.com/profile/14663293800162306859noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-76880487056423331282020-03-28T18:05:47.939-07:002020-03-28T18:05:47.939-07:00We've been fighting it in our house for going ...We've been fighting it in our house for going on 3 weeks Mon. <br /><br />Everyone in our house is in great physical shape. None hi risk.<br /><br />It is a tough bug.<br /><br />Textbook 'mild flu' symptoms for us. No crashers. Just getting better sooooooooo slowly.<br /><br />No fevers, breathing difficulties, nose problems, etc.....just major, major aches, fatigue, and trouble thermo regulating.<br /><br />One or two hours work / day which for us is 90% less than normal capacity.<br /><br />Get yer big jobs done when you feel well.<br /><br />Get ready to sleep better than twice than normal.<br /><br />Eat best you can, take your vitamins with extra C, D3, zinc.<br /><br /><br /><br />Adinohttps://www.blogger.com/comment.g?blogID=714028479313834812&postID=7902221561342700949&bpli=1noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-17140906294494089512020-03-28T17:59:50.340-07:002020-03-28T17:59:50.340-07:00Stefan said...
@ Aesop
You mean like we used to do...Stefan said...<br />@ Aesop<br />You mean like we used to do for TB, Plague, Smallpox, Polio, Measles and SpanFlu? Those were real sure 'nuff Problems. Somehow they went away without living on Cellblock E.<br />--------------------<br />Somehow they went away back when a horse was considered speedy travel.<br />Harleqwinhttps://www.blogger.com/profile/15226526359579486937noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-92178526078915290852020-03-28T14:00:31.313-07:002020-03-28T14:00:31.313-07:00@ Aesop
You mean like we used to do for TB, Plague...@ Aesop<br />You mean like we used to do for TB, Plague, Smallpox, Polio, Measles and SpanFlu? Those were real sure 'nuff Problems. Somehow they went away without living on Cellblock E.<br /><br />Coming up soon....a Scheißkopf Medal, for the hypochondriac paranoids like me that really do isolate and use PPE and disinfect.<br /><br />Except you don't get a ribbon, or a thank you, just stupid looks, snide comments, and reputation-murder (in German called Ruf-Mord, a litigatable offence, if you can get it proved). In English it's slander, malicious rumour, defamation. Back when honour was real, we killed or died for it.<br /><br />If the Granny on my corridor gets it and dies, it won't be from me. If any of the 95 other households in my building gets it, it won't be because I was too proud or cowardly to wear goggles and a N100 mask and carry and use 75% ethyl alc. Surprised building management hasn't posted any notices, or even encouraged the "cleaning" ladies to run a rag over the lift buttons for the first time the new lifts were installed 3 months ago. Which brings me to...<br /><br />LAWYERS. How much of the stupid difficulties we see rear their peculiar heads these days are motivated by a fear of being held LIABLE, or skating past on That's Not My Job. Given that there seems to be built into Corona a Get Out Of Jail OMG Unprecedented Hysteria Oh My The Vapours Card.<br /><br />Good, I've got my self righteous Scheißkopf Medal, and am at least thankful it wasn't Something Serious. Now I'm thinking of stuff to do now to forestall worse disasters, perhaps even Volunteering my efforts in some effective way to rebuild.<br /><br />Now, is it going to be directly reconstructive, or temporarily destructive? Change a diaper, or cut a throat? Too early to say...so I make sure I clean my own diaper and avoid burdening someone else, and sharpen my knives. Aesop, I tip my visor to you and your colleagues. Won't blame you if you cut out and set up a tent hospital for Anything But CoV, and fill a ditch out front with Viridiots.Stefanhttps://www.blogger.com/profile/14663293800162306859noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-56223052582485647502020-03-28T13:14:04.415-07:002020-03-28T13:14:04.415-07:00@ga6,
I read exactly what the ER doc wrote. 86% d...@ga6,<br /><br />I read exactly what the ER doc wrote. 86% death rate for intubated patients is worldwide. 70% death rate for intubated patients is results from Seattle.<br />QED<br /><br />@Stefan,<br /><br />If we could isolate <i>everyone</i> for 14 days, and identify all the infected carriers, and isolate <i>them</i> for 30 days, this would be over worldwide on May 1st. <br />Done. Kaput. Gone.<br /><br />But we can't do that.<br />And people are Scheißköpfe.Aesophttps://www.blogger.com/profile/07834464741531503378noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-58838394888196253272020-03-28T12:45:00.707-07:002020-03-28T12:45:00.707-07:00The current muted Krap-Fest here in Teutonia mostl...The current muted Krap-Fest here in Teutonia mostly came from the ski folks in a few nodes in Austria. R-naught, as Dr Campbell tells us, is a combination of the virus' innate capabilites, and the behaviour of its carrier....a hoooman. Isolate, so you don't spread it, and kill all the Grannies and fat smokers, and the medical system. Isolate, so this Krap-Fest dies fast, and the Vultures making profit off it don't make quite as much. It needs a small amount of discipline and self sacrifice, which is why we are bent over the hood getting an unlubed proctological with a splintery chairleg.Stefanhttps://www.blogger.com/profile/14663293800162306859noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-56156344927450241452020-03-28T12:42:47.741-07:002020-03-28T12:42:47.741-07:00Try this one: hospitals and Old-Age Nursing Homes...Try this one: hospitals and Old-Age Nursing Homes are the vectors. South Korea instituted a new protocol for MD/RN (etc) personnel: wash hands before and after patient contact AND before and after touching anything which may carry virus.<br /><br />It's not a slam on med personnel. It's a reasonable theory.<br /><br />Thought you'd like to think about that given your knowledge of med facilities.Dad29https://www.blogger.com/profile/08554276286736923821noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-64629541668385817792020-03-28T12:24:20.536-07:002020-03-28T12:24:20.536-07:00For an old man how did you arrive at a 84% death r...For an old man how did you arrive at a 84% death rate, what figures are you using above and below the line?ga6https://www.blogger.com/profile/06995898324916115728noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-34962341458807052772020-03-28T11:59:04.751-07:002020-03-28T11:59:04.751-07:00@Tim,
OBE: Overtaken By Events. Doc reports 0% suc...@Tim,<br />OBE: Overtaken By Events. Doc reports 0% success with that approach.<br />If it work at all, it's only working early.<br />Late is too late.<br /><br />@Rick C: Yes, 70-86% death rate <i>for intubated patients</i>, <b>not</b> all patients. IOW, it's a total waste of time between 2 times out of 3, and 6 times out of 7.<br /><br />@OldNFO,<br />Dunno either, but it's there, and that's how it looks with the blinders off.<br />It for sure isn't going to be prettier in non-Mardi Gras cities.<br />Shit Mardi Gras is everywhere this is, unless you starve it off and wipe it out.<br />Aesophttps://www.blogger.com/profile/07834464741531503378noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-55994038738381502622020-03-28T11:20:45.799-07:002020-03-28T11:20:45.799-07:00Thanks for the update. Front line data is always g...Thanks for the update. Front line data is always going to be rough. I can't help but wonder if this hot spot IS a product of Mardi Gras... Friend is an LEO down there, they are being VERY careful how they handle all interactions. They have very limited PPE.Old NFOhttps://www.blogger.com/profile/16404197287935017147noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-16378549463361382142020-03-28T10:39:40.932-07:002020-03-28T10:39:40.932-07:00"70-86% death rate, even with ventilator ther..."70-86% death rate, even with ventilator therapy?"<br /><br />Unless I misread, isn't that the percentage of people <b>on ventilators</b> who die, not total patients?Rick Chttps://www.blogger.com/profile/10992428161064901136noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-31957175700863451132020-03-28T10:01:38.884-07:002020-03-28T10:01:38.884-07:00This:
https://uslibertywire.com/ny-doctor-succe...This:<br /><br /><br /><br />https://uslibertywire.com/ny-doctor-successfully-treats-patients-with-drug-cocktail-zero-deaths-zero-hospitalizations-zero-intubationsTim in Evergreennoreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-36049729559924091042020-03-28T09:02:31.834-07:002020-03-28T09:02:31.834-07:00Everything I've anecdotally observed about ant...Everything I've anecdotally observed about anti-virals for <i>acute</i> viral infections is that they only make a difference if given early. Like the ones for flu, or shingles, it's official for them, oseltamivir/Tamiflu, first 48 hours, acyclovir/Zovirax or its prodrug, 72 hours.ThatWouldBeTellinghttps://www.blogger.com/profile/16910231314995266781noreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-15277006672393023562020-03-28T08:32:13.260-07:002020-03-28T08:32:13.260-07:00This ....
https://www.zerohedge.com/geopolitical/...This ....<br /><br />https://www.zerohedge.com/geopolitical/escobar-why-france-hiding-cheap-and-tested-virus-cure<br /><br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-45070549265715991172020-03-28T08:03:49.514-07:002020-03-28T08:03:49.514-07:00A cynical thought. Chloriquine compounds are all ...A cynical thought. Chloriquine compounds are all Generic Medications. There is not much money to be made if the treatment is effective. Could they be using the medical trial methodology to make the treatment less effective? Delay the treatment by requiring a confirmed lab test, where many of these tests do not provide the results for several days? That gives the Chinese Coronavirus a lot of time to reproduce, further sicken, and even to kill the patient, all while you patiently wait for an overloaded lab to report the test results? Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-71093820671629947552020-03-28T07:54:58.920-07:002020-03-28T07:54:58.920-07:00There was a graphic on page 3/5 that showed the pr...There was a graphic on page 3/5 that showed the prophylaxis dosing schedule for both Chloriquine and Hydroxy Chloriquine supposedly the schedule was from India? The medical papers that investigated Chloriquine compounds all emphasized that the purpose of the Chloriquine was to get ZINC into the cells where it disrupted the ability of the virus to reproduce. Chloriquine doesn't seem to kill the virus itself, nor does it kill the infected cell, it does prevent it from making millions more virii / viruses. <br /><br />I think the problem using Chloriquine is that they are using it too late. Someone above mentioned that too. Scott Adams Says discussed the in Episode 871 of his podcast. (He also mentioned some doctors are prescribing it for family and friends). The purpose of the Chloriquine and Zinc is to stop the virus reproduction early, before it gets a damaging foothold. Just like penicillin won't do much for your leg injury, if your leg is already swollen, black, and gangrenous. Waiting to start the Chloriquine treatment only after the Chinese Coronavirus infection is confirmed by lab test is probably a bad thing. Start them on the Chloriquine and Zinc immediately, and discontinue if the test is negative. People have died while waiting for the lab test results. Also what happens if the test is a false negative? <br /><br />I am Hoping they are finding other therapies that are more effective against the late term infections. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-714028479313834812.post-52693809188094214612020-03-28T07:39:57.889-07:002020-03-28T07:39:57.889-07:00This does NOT sound good.This does NOT sound good.Borepatchhttps://www.blogger.com/profile/05029434172945099693noreply@blogger.com